Transplant Immunosuppressive Drug Trials on Trial
نویسندگان
چکیده
منابع مشابه
Antimicrobial and immunosuppressive drug interactions in solid organ transplant recipients.
Infections are frequent and can be severe in recipients of solid organ transplantation. Prevention and treatment are priority objectives of multidisciplinary transplant teams. Interactions between antimicrobials (indicated for prevention and therapy) and immunosuppressants (for preventing rejection) make treatment more complex than in the general population. Co-administration of immunosuppressa...
متن کاملImmunosuppressive Drugs and Kidney Post-transplant Diabetes Mellitus
Background: As the rate of renal transplantation increases, more immunosuppressive drugs such as cyclosporine A (CsA) are consumed, particularly during the early months following transplantation, leading to post-transplant diabetes mellitus (PTDM) which can cause death. Objective: The present study examined the role of CsA in causing PTDM and other effect...
متن کاملEffect of Immunosuppressive Drugs on Humoral Allosensitization after Kidney Transplant.
The negative effect of donor-specific antibodies on the success of solid transplant is now clearly established. However, the lack of effective treatment to prevent the development of antibody-mediated lesions deepens the need for clinicians to focus on primary prevention of de novo humoral allosensitization. Among the factors associated with the risk of developing de novo donor-specific antibod...
متن کاملImmunosuppressive drug therapy.
The first successful kidney transplantation between monozygotic identical twins did not require any immunosuppressive drugs. Clinical application of azathioprine and glucocorticosteroids allowed the transfer of organs between genetically disparate donors and recipients. Transplantation is now the standard of care, a life-saving procedure for patients with failed organs. Progress in our understa...
متن کاملTuberculosis in renal transplant recipients on various immunosuppressive regimens.
BACKGROUND Mycophenolate mofetil (MMF) and tacrolimus (TAC) are more potent than conventional immunosuppressive drugs, i.e. azathioprine, cyclosporin and prednisolone, and may be associated with an increase in the incidence of infections in the post-transplantation (post-tx) period. The aim of this study was to determine if the use of either or both of MMF and TAC for immunosuppression in renal...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2004
ISSN: 1600-6135,1600-6143
DOI: 10.1111/j.1600-6143.2004.00474.x